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If there is one candidate that fits that bill to explain my description, it would be inhibition of AMPK, the master regulator of metabolism (2)

After taking the daily pill for about 15 months, heres what participants experienced: Average weight loss of 13.6% across all participants, even those who werent perfectly consistent 16.6% average loss when the medication was taken consistently More than 3 out of 4 participants lost at least 5% of their body weight About 1 in 3 hit the 20% mark or higher But the benefits went beyond what the scale showed

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